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Benchtop Particle Beam Interface |
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| Particle Beam LC/MS |  |
| CSS Analytical Particle Beam Interface for Agilent 5973/75 MSD or your EI mass spec. This Benchtop LCMS system is an excellent tool for the analysis of samples where traditional LCMS techniques such as electrospray or apci, have special difficulties. Or, for when it is necessary to positively identify your results by comparing them to a commercial library of mass spectral data.
As a complimentary technique to your existing ESI instrument. When additional or different information is needed, you already have the chromatography worked out. Send the same vial, using the same column and mobile phase conditions to the particle beam and get library searchable EI spectra.
In our most recent paper, "Identification of Antineoplastic and Neurotrophic Lignans in Medicinal Prairie Plants by Liquid Chromatography Electron Impact Mass Spectrometry (LC/EI/MS)" we have confirmed the identity of a potential cancer-fighting agent that could verify the purported activities claimed by the Plains Indians of a particular medicinal plant. The use of the CSS Analytical Particle Beam Interface permits the rapid assessment of plant extracts for the presence of medicinally active compounds with a minimum of pre-purification.
In the case of environmental PNA’s you can ionize the sample without difficult and time consuming hplc modifications required with electrospray or apci.
In the cases where unknown peaks may be encountered or legal defensibility is a necessity, for example in pharmaceutical development, drugs of abuse or forensics. Such a case is with a sample like the St. John’s Wart. Here even though electrospray or apci do an excellent job of detecting the peak, the information contained in the spectrum may be found lacking when a positive identification is needed. For this reason the power of library searching an electron impact spectrum becomes apparent.
For sensitivity, separation, and identification purposes the CSS Particle Beam and Agilent Technologies, Inc. 5973/75 Benchtop LCMS system is an excellent choice.
The particle beam interface, long forgotten by commercial vendors could still play an important role in your research. Contact us today for more information !
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Click here to contact a CSSCO specialist about your product needs! |
Check out some of our papers using the particle beam interface:
Article Published in American Laboratory & American Biotechnology Laboratory: June/July 2007 Volume 25, Number 7: Identification of Medicinally Active Compounds in Prairie by HPLC Coupled to Electron Impact-Mass Spectrometry. American Bio Lab July 2007.pdf
 PITTCON 2007.pdf (49.89 KB) Reprint of Poster from PITTCON 2007: Breakthrough in Quantitation and Linearity in Particle Beam LC/MS through Improvements in Aerosol Generation and Particle Transport.
ASMS 2006.pdf (44.93 KB) Reprint of Poster from ASMS 2006: Characterization of Di- and Tri-substituted Sulfonated Azo and Acid Dyes by LC/ESI/MS/MS, LC/EI/MS and LC/CI/MS.
KC Life Science 2006.pdf (286.53 KB) Reprint of Poster from Kansas City Life Sciences Day 2006: Identification of Antineoplastic and Neurotrophic Lignans in Medicinal Prairie Plants by Liquid Chromatography Electron Impact Mass Spectrometry (LC/EI/MS).
P 2006 Tannin.pdf (110.27 KB) Reprint of Poster from PITTCON 2006 Application of LC/ESI/MS and LC/EI/MS to the Characterization of Tannins and Flavonoids from the Acorns of Quercus macrocapra P 2006 Monarda.pdf (113.42 KB) Reprint of Poster from PITTCON 2006 Analysis of Antioxidant Polyphenolics in Medicinal Plants by GC/MS and LC/EI/MS
tp316.pdf (302.94 KB) Reprint of Poster ThP316 for ASMS 2005 Chemical Constituents of Acorus calamus from a Kansas Prairie cp05.pdf (195.41 KB) Reprint of Corporate Poster for ASMS 2005 The Self Oscillating Nebulizer cssOCN© for all brands of LCMS and ICP
pittcon2005a.pdf (144.50 KB) Reprint of Poster for PITTCON 2005 The Analysis of Red Bell Pepper Constituents by Particle Beam Liquid Chromatography Mass Spectrometry
1945poster.pdf (88.54 KB) Reprint of PITTCON 2001 Poster (Tuesday 1945P) A Comparison of Information Contained in the Spectra of LC/MS Electron Impact (EI), Chemical Ionization (CI), and Electrospray Ionization (ES) for selected chemicals and natural products.
87poster.pdf (7.52 MB) Reprinted presentation of PITTCON 2001 Oral Presentation (Monday 87O) What to do with the “Leftovers”’ An Effective Method for the Determination of Intermediates and Products in an Open Access Environment that don’t work by ESI LC/MS. This is a large file, 7.6 MB
poster211.pdf (170.49 KB) Complete ASMS 2000 Poster (ThP211) as presented, entitled: Application of a Particle Beam LC/MS Interface to the commercially available Agilent 5973 Mass Spectrometer.
poster236.pdf (150.48 KB) Complete ASMS 2000 Poster (TP236) as presented, entitled: A comparison of the structural information contained in the LC/MS EI and CI spectra of selected chemicals and natural products.
pbeam01.pdf (1.02 MB) Application of particle beam interface to Agilent 5973 benchtop mass spectrometer showing analysis of PNAs and an extraction of St. John's Wort.
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