It is now possible to take full advantage of easy, repeatable nano spray using the the Agilent Chip product with Thermo LTQ, Velos, Orbitrap, Q Exactive or Vantage triple quadrupole mass spectrometers.  An Agilent HPLC-Chip Cube MS Interface (G4240A) is modified by CSS Analytical Co Inc. and with a custom built interface, it easily attaches to any Thermo Scientific mass spectrometer with an IonMax source housing. The Agilent Chip (various part numbers) is a credit card sized, disposable product, which offers an enrichment column, an analytical column, a column switching valve and an electrospray (ESI) emitter – all on one micro-fabricated chip.